30574.銅催化ch鍵活化cno偶聯反應研究

1、論文指導小組成員組長：楊仕平教授組員：楊仕平教授楊紅教授吳惠霞教授周治國副教授ThesisTitle：CoppercatalyzedAromaticCmHActivationofC—N／OCouplingReactionThesisType：AppliedresearchSpecialty：InorganicChemistryDegreeApplicant：HuiXuInstructor：DrzengmingShenProfhongYa

2、ng，AbstractAcoppercatalyzedaromaticC—】Hbondactivationfort11eformationofC—1、I／C一0bondshasbeendevelopedWefoundthebestconditionsfortllecatalyticC—NformationarecheapCuOAcasacatalystunderanoxygenastheterminaloxidantintheprese

3、nceofmixedtolueneandOdichlorobenzene，Undertheseconditions，theamidationreactionofaromaticC—HbondsCanbesuccessfullyperformedEitherelectronrichorelectronpoorgroupsonaryltingsgavethecorrespondingproductswitllmghefficiencyFor

4、themechanisticstudies，radicaladditivesexperimentswereconductedandindicatedthatsomeradicalinhibitorssuchasBHT14dinitrobenzenedidn，taffectonthesereationsAsaresult，werutedoutthepossibilityofradicalpathwaysforCucatalyzedC—Ha

5、midationInaddition，KIEexperimentsshowtheC_HbondactivationstepisratedeterminingstepofthereactionIntertesinglywefoundlittleimprovementofreactionconditionstobeapplicableforthearomaticC—Hetherificationwithalcoholasacouplingp

6、aterInthissystem，cheapcoppersalt，greenandenvironmentallyfriendlyoxygenasoxidant，andcatalyticamountofbenzoicacidasaadditivewithoutaddingotherexcessoxidantweretheoptimalconditionsforC—旬formationUndertheseconditions，awidera

7、ngeofelectronrichandelectronpoorsubstrated3methyl一2一phenylpyridineallprovidedtheproductsingoodyieldsTheprimaryalcoholsandsecondaryalcoholsarealsoperformedwellinthissystemKeywords：copper；C—IHactivation；C—_Ncouplingreactio