不同條件下小鼠子宮內(nèi)膜中HOXA-10的表達(dá)及子宮內(nèi)膜容受性的變化.pdf

1、大連醫(yī)科大學(xué)碩士學(xué)位論文不同條件下小鼠子宮內(nèi)膜中HOXA10的表達(dá)及子宮內(nèi)膜容受性的變化姓名：高國強(qiáng)申請學(xué)位級(jí)別：碩士專業(yè)：婦產(chǎn)科學(xué)指導(dǎo)教師：石紅20090601ExpressionofHOXA10GeneintheEndometriumofMouseandChangeofEndometrialReceptivityinDifferentConditionsMasterdegreecandidate：GaoGuoqiangSupervi

2、sor：ProfessorShiHongMajor：ObstetricsandGynecologyAbstractObjective：ToexaminethedifferentexpressionofHOXA10inthenonpegnentandpregnantgroupofmiceendometrium，anddiscussdifferentfactors(ovarianstimulateddrugs，semenandembryo)

3、influenceonexpressionofHOXA10andsignificanceMethods：Themiceweredividedintononpregnantgroups(includingnature／unstimulatedcyclegroup，ovarianstimulationgroup，bilateraloviductsligatedgroup)andpregnantgroups(unilateraloviduct

4、ligatedgroup)ReservetranscriptionPCR(RTPCR)separatelyexaminesHOXA10inmouseendometriumofpregnantD27fromeverygroupandmakesanalysisResults：Bothnon—pregnantandpregnantgroupshaveHOXA一10expression，butthereisobviouslydifferentb

5、etweenthem1Innatureperiodgroup，HOXA10ispositiveinsecretoryendometriumandexpressionintensityisnotobviousdiversificationinmatedD27(P005)2Comparedtonatureperiodgroup，HOXA10isnodifferenceinovarianstimulatedgroupandbilateralo

6、viductsligatedgroup(P005)3Inpregnantgroup，expressionofHOXA一10raiseupdistinctlyinD3，achievethepeakvalueinD4(P005)，droptobaselineinD7，equaltowindowofimplantationExpressionofHOXA10inpeakplatformperiodprolongs(D45)anddecline

7、sslowlyinpregnantendometriumTheexpressionruleofHOXA10inleftnonpregnantgroupisthesanleasrightpregnantgroupConelusion：IHOXA—10haskeyeffectondifferentiation，decidualizationofendometrialcellandformationendometrialreceptivity