胃癌、胃癌前病變、慢性胃炎的拉曼光譜研究.pdf

1、蘭州大學(xué)碩士學(xué)位論文胃癌、胃癌前病變、慢性胃炎的拉曼光譜研究姓名：楊婉容申請學(xué)位級別：碩士專業(yè)：消化內(nèi)科指導(dǎo)教師：許蘭濤20100601蘭州大學(xué)碩二t研究生學(xué)位論文Abstractgastriccancerisoneofthehighestincidenceofcancerinworldwide，whichisthesecondcommoncancerinChinaThereareabout900，000newcasesofgastri

2、ccancerintheworldeveryyear，Atthesametime，70millionpeoplediedofstomachcancerTheoverall5yearsurvivalrateofgastriccancerisabout20％，Theincidenceofmenis15to25timesmorethanthewomenTheincidenceofgastriccancersignificantlyincrea

3、seswithage，thepeakincidenceinagefrom50to80yearsoldTherefore，earlyexamination，earlydiagnosisandearlytreatmentistheoneofkeymeansinreducinggastriccancermortalityNow，thediagnosisofgastriccancerismainlyrelyontheendoscopyandbi

4、opsyspecimens’Spathologicalexaminationobtainedbyendoscopic，However，thepathologicalexaminationwi11spendofalongerperiod，whichisalsoincreasedthemedicalcostsTherefore，findamoresimpleandaccurateinspectionmethodsarealsoveryimp

5、ortantRamanspectroscopyisoneoftheavailableopticaltechnologies，Themalignanttissuesandcellsarealwaysfromthetheirmolecularcomposition，inthemalignanprocessoftissuesandcells，thetypesofchemicalsthatcompositeofvariousbiological

6、cellandtissuewilltochangeinquantity，structure，conformationandtheexistenceofthestateduetoThevibrationalspectroscopymethodscanbereflectedthestructureofmatterandchangesatthemolecularlevel，Bytrackingtheorganizationmalignantc

7、hangesinthemolecularleveltobecometheearlydiagnosisoftumorsnewmethodsAtpresent，somescholarshavecarriedoutspectralstudieinthelungcancer，livercancer，esophagealcancerandbreastcancer，Alsoconfirmedthatthecanceroustissueandnorm

8、altissuehavethedifferencesinthespectralperformance，Onthisbasis，wewilltodofurtherresearchonthedifferenceinthegastriccancer，gastricprecancerouslesionsandchronicgastritisorganizationsObjective：TheuseofRamanspectroscopyinpat