Ⅰ-Ⅱ期宮頸癌盆腔孤立性淋巴結(jié)轉(zhuǎn)移對(duì)預(yù)后的影響及其高危因素的分析.pdf

1、福建醫(yī)科大學(xué)碩士學(xué)位論文ⅠⅡ期宮頸癌盆腔孤立性淋巴結(jié)轉(zhuǎn)移對(duì)預(yù)后的影響及其高危因素的分析姓名：戴藝芳申請(qǐng)學(xué)位級(jí)別：碩士專業(yè)：婦產(chǎn)科學(xué)（婦科腫瘤）指導(dǎo)教師：鄭秀20100401PrognosticimpactandriskfactorsofsolitarylymphnodemetastasisinstagesI。—IIcervicalcarcinoma[Abstract]ObjectiveToanalyzetheprognosticimpa

2、ctandRiskFactorsofsolitarylymphnode(LN)metastasisonCervicalCarcinomaMethods188patientswithdiagnosisofstageIA—IIB(FIGO)cervicalcancerwereprospectivelystudiedfromJanuary1999toDecember2005，188patientswithcervicalcancerunder

3、wentradicalhysterectomyandpelviclympha—denectomyAmongthem，43wereprovensolitarylymphnodemetastasispathologically(solitaryLNmetastasisgroup)，while145provennodenegativemetastasis(node—negativegroup)The5yearsurvivalrateswere

4、comparedbetweensolitaryLNmetastasisandnode—negativegroupsTheprognosticfactorswereevaluatedbyunivariateandmultivariateanalysesThemultivariateanalyseswasusedtostudytherelationshipofclinicalandpathologicalfeaturesofcervical

5、carcinomawithmetastasisofpelviclymphnodeResultsThe5yearsurvivalratesofsolitaryLNmetastasisgroupandnode—negativegroupwere512％and841％respectively，withsignificantlydifference(PO05)ThesolitaryLNmetastasiswasoneoftheindepende

6、ntprognosticfactorsforthepatientsenrolledLogisticregressionrevealedthatthedepthofinvasion，clinicalstageandlymphvascularinvolvementwereindependentcovariatesforsolitaryLNmeta—stasiSConclusionsWhenpatientshadsolitaryLNmetas

7、tasis，theprog—nosisofthemwassignificantlyworsethanthosewithoutlymphnodemetastasisThemajorriskfactorsoflymphnodesmetastasiSincervicalcarcinomaaremuscularinfiitratio，lymphvascularinvolvementandclinicalstage[Keywords]：cervi