還原烷基化合成(β-羥乙砜基)-N-乙基苯胺研究.pdf

1、大連理工大學碩士學位論文還原烷基化合成(β羥乙砜基)N乙基苯胺研究姓名：楊海燕申請學位級別：碩士專業(yè)：精細化工指導教師：吳祖望20000601ABSTRACTABSTRACT3(8hydroxyethyl—sulfonyl)N—ethylanilineand4一(0一hydroxyethylsulfonyl)NethylanilineareimportantintermediateforbifunctionalreactivedyesA

2、nethylgroupintroducedonthebridgenitrogenatomoftheMCT／VSbifunctionaldyepossesseshigherreactivitygoodpermeabilityandbuid—uppropertiesandbetterfastnesstochlorinebleachthanthatofiminobridge(noethyl)dyesReductivealkylationof3

3、(Bhydroxy—ethylsulfonyl)anilinewithacetaldehydeandhydrogeninthepresenceofRaneynickel，morethan98％conversionand945％selectivityofmonoalkylationwereachieved，Toprepare3一(13hydroxyethylsulfonyl)一N—ethylanilinefrom3一(B—hydroxye

4、thylsulfonyl)nitrobenzenewithhydrogenandacetaldehydeinthepresenceofRaneynickelbyonepottwostepsmethod，98％conversionratioand97，5％selectivityof3f13一hydroxy—ethyl—sulfonyl)一N—ethylanilinewasgivenSynthesizing4(13一hydroxy—ethy

5、lsulfonyl)N—ethylanilinefrom4一(13hydroxyethyl—sulfonyl)一acetyl—anilineviahydrolysisandreductivealkylation，theyieldof4(B—hydroxyethylsulfonyl)一anilinewas9094％；theconversionandselectivityofreductivealkylationwere95％and97％r

6、espectivelyThesinglecrystalsoftwoModelcompounds，24一dimethoxy一6一anilino—triazineand24dimethoxy一6rNmethyl—anilino)triazinewereobtainedWhichweredeterminedonCD4X—rayDeflectorThedataindicatedthattheplanarangleoftriazineandphe