CA19-9在卵巢成熟囊性畸胎瘤診斷中的臨床意義.pdf

1、山西醫(yī)科大學碩士學位論文CA199在卵巢成熟囊性畸胎瘤診斷中的臨床意義姓名：任茂華申請學位級別：碩士專業(yè)：婦產科學指導教師：史小榮20100415山西醫(yī)科大學七年制臨床醫(yī)學碩士專業(yè)學位論文AbstractBackground：Manlrecysticteratomaoft：【leovaryisthemostcommongynecologicalcancer，ovariancancerinciderlceacco吼tedforl0％to2

2、0％，acco叫ingfor85％ofgemceUsto97％，accountingfor95％ofteratomaSGmoccuratanyage，mostlv20t040yearsoldMostlyuIlil納eral，bilateral，10％一l7％Mali凹鋤ttransformationrateofl％to3％(morecommoninpostmenopausalwomen)AreoIllyafewstudiesoftuII

3、lormarkersinthedia駔osisofmatlJreteratomainttleroleCAl99aIltigen向rtheg筋trointestinal位俄’butaSatumormarkerwidelyusedingynecologyStudiesonserumlevelsofCAl99inmaturecysticteratomaiIlthedia盟osisofoIllyafewarticIessof打athomeand

4、abroadareStillreported，也esereportsshowthatpatients誦mma_turecySticteratomaCAl99istheonlVelevatedtumormarker，inc∞ased45％to59％hlrecentyears，domesticrelated仃anslatioIlsa11dalsotllatoftlleCAl99diagnosisofmaturecysticteratomis

5、allimportantindicator，itsvalueincreaSed嘶thtumorsize，one弱sociated研thbilateralce蹦nCA199maybetllediagllosisofoVariallman鵬cysticteratomaisaIlimponamttu】mormarkerObjective：Tballalyze83c嬲esofmaturecySticteratomainpatientswitll

6、serllmlevelsofCAl9—9values，assessitsrelationsllipwithtllmorsize鋤dpatientageatonsctofunilateralaIldbilateraIrelationsMethods：FirstHospitalofShall)【iMedicalUniversity，2ynecologicalJallu習眄2007～May2009hospitalizedpatientswit

7、Ilma：turecysticteratomacompletemedicalrecordswerereviewedretlospeCtively83c嬲esByCAl99Ⅶlues、Ⅳeredividedinto似。印ups，n鋤ely，eleVatedCAl9—9Values(鏟oupI)andCAl9—9valueofthenornlal舀oup(groupII)，咖gr01叩sofpatientsbe鉚eenmeageofonse

8、t，tumorsize，singleaIlddoubleside，aJldtheincreasedrateoftllIl】ormarkerS、ⅣerecomparedAlldatawerea11alyzedusingSPSSl60paCkage，謝th士Ssaidmeasu崩nentda：tabe鉚eentlle咖groupsusingtteStaIldrankslⅡntest，PO05、w峪sig田ificantResults：(1)

9、TlleaVerageageof371士121years(rallge14to69yearsold)，groupIaVerageageof352l1340yearS(rallge1469years)，groupIIaVerageageof39561023years(mge1957years)(2)theaVeraget哪ordi鋤eterwaS82士32cm(range3～22cm)，舯upIaVeragedi鋤eterof927士34

10、7cm(range5～22cm)，di鋤eter芝8cmaccountedfor6905％，鯽upIIaveragediameterof7323士277cm(range3—10cm))，diameter芝8cmaccoumedfor3902％(3)unilateralt啪orincidencewaS8433％，unilateralrateof8434％ingroupI肌dgroupIIllIlilateralrateof8780％(4)

11、theaveragelevelofserumCAl9—9waS5201士5531U／L(ra咀ge104～24525U／L，normal30U／L)，increaSedrateof5060％；meansemmCAl25levelw嬲1690士233lU／L(啪ge296—20211U／L，normal35U／m1)，increasedrateof521％，higherrateof476％ingroupIandgroupⅡincreaSe

12、drateof732％：meaIlsen_lIllCEAlevelw弱136士087Ug／L(r趿ge01～2042Ug／L，nomal15Ug／L)，increasedrateof241％，lligherrateof476％iIlgroupIa11d甜oupHincreasedrateof0％：meallsenⅡnAFPlevelwaS243士162Ug／L(mgeO4—2206Ug／L，nomalQ0Ug／L)，increasedr

13、ateofl20％Hi曲errateof234％mgroupIaIld舀oupIIincreasedrateof0％Conclusions：(1)elevatedlevelsofserumCA199werelargertumordiameter但)tullIlorSwasuIlilateral，andⅡleIevelofser哪CA199鋤dothertuIIlormarkershadnelationship(3)ovarianmatu