山仙顆粒對S180肉瘤細(xì)胞轉(zhuǎn)染的昆明小鼠BCL-2和BAX基因表達(dá)影響的實(shí)驗(yàn)研究.pdf

1、學(xué)院代號。，∞716●。___●_。___^_●__●_●___●_______一專業(yè)代碼；；i00802學(xué)號003121401039密級：1i|『jj。。≯萋jj毫◆薯陜西中醫(yī)攀，院ShaanxiUniveI_sity0fChineseMedicihe碩士學(xué)位論文山仙顆粒對SiS0肉瘤細(xì)胞轉(zhuǎn)染的昆明i小膩————————————●—————————————————————————__——_■上—一——BCL2和BAX基因表達(dá)影響的實(shí)驄

2、研究j!每i黻申請人。‘：，慧矗、，，專‘i!；孵≯名i稱申謹(jǐn)。學(xué)穰類型一‘指導(dǎo)教一師i姓。名史迎莉中西醫(yī)結(jié)合舔床t專業(yè)學(xué)位陳光偉主任醫(yī)師n。o一?！觥鯻：■——_—’——論文提一一京。雕斯薯。黔。露澎006年5雕“r鞲饕爹——————～Title：TheexperimentalresearchwhichShanXianGranuleeffectedtheexpressionofBcl2andBaxinkungmingmicetrans

3、ferredbySarcoma180eel1ABSTRACTobjectiv：TOinvestigatethelevelofBcl2andBaxinKungmingmicetransferredbySarcoma180cell，andtoexplaintheanti—growthofthemalignanttumoroftheShanXianOranule(SXG)Method：40miceweredividedinto4groupsr

4、andomlyAwastheblankcontrastgroup，andB，C，DweremadeintomodelgroupsThenextdayaftermakingmodel，eachofC，DgroupsweregivenJinLongCapsule(JLC)andSXGseparatelyandA，Bgroupswerenormalshine21dayslater，weputthosemicetodeath，thendetec

5、tedthelevelofbcl一2andbaxbyusingirnmunothistochemicalmethodintransplantedtumorofS180cellAtthesanletimetesttheothertargetsResult：Thetimeofthetunlorcomingintobeing，theweightofthetransplantedtBmorandmice，thelevelofBel一2andBa

6、xintransplantedtunlorofC，DgroupsincontrastofthoseofBgroup，thedifferenceWasprominent(pO05)Conclusion：SXGcallresistthegrowthofS180SarcomaIt、SmechanismofresistinggrowthmostcorrelatewimlowingthelevelofBcl2andincreasingexpres