早產(chǎn)兒視網(wǎng)膜病變組織形態(tài)學觀察.pdf

1、復旦大學碩士學位論文早產(chǎn)兒視網(wǎng)膜病變組織形態(tài)學觀察姓名：費萍申請學位級別：碩士專業(yè)：眼科學指導教師：趙培泉20030501復旦大學碩I。學位論文英文摘要MorphologicalStudyofRetinopathyofPrematurityAbstract[Purpose]r10studythepathologicalcharacteristicsofretinopathyofprematurity(ROP)，anddiscussthe

2、pathogenesisofROR[Methods]1Thirty—fourlensesandepiretinalfibrovascularmembranesobtainedfromtwentyfourROPpatientsduringopenskyvitrectomywereexaminedbylightmicroscopy(HEstaining)，and／ortransmissionelectronmicroscopy2GFAPst

3、ainingoftheepiretinalmembraneswereobserved[Results]1，TherewasnoobviousabnormalityofthelensesinROPpatiems2CollagenwasthemaincomponentoftheepiretinalmembraneThenumberofthefibroblastsvariedindifferentspecimensItisrelatedtot

4、hegestationalageandpostconceptionalageThenumberofneovasculehadrelationshipwithageandpostconceptionalageBothofthemhadnothingtodowithbirthweightNoobviousrelationshipwerefoundbetweentheoperationresultsandclinicalfactors3Ele

5、ctronmicroscopyshowedawidevarietyofcelltypes，whichwerescatteredthroughthemembrane，includingflbroblasts，myofibroblasts，vascularendothelialcells，macrophagesandotherinflammatorycells4GFAPstainingoftheflbrovascularmembranewa

6、spositive，andstainingpositivecellsweremostlydistributedontheretinasideofthemembrane[Conclusions]1Prematurityhadnoobviousinfuenceonthedevelopmentoflens2Fibroblastsandmyofibroblastsweremaincellsintheepiretinalfbrovascularm