卡馬西平誘導兒童良性癲癇伴中央顳區(qū)棘波出現(xiàn)癲癇性電持續(xù)狀態(tài)的初步研究.pdf

1、分類號：R725.8密級：公開UDC：610學校代碼：11065碩士學位論文卡馬西平誘導兒童良性癲癇伴中央顳區(qū)卡馬西平誘導兒童良性癲癇伴中央顳區(qū)棘波出現(xiàn)癲癇性電持續(xù)狀態(tài)的初步研究棘波出現(xiàn)癲癇性電持續(xù)狀態(tài)的初步研究黃啟坤黃啟坤指導教師華青副教授學科專業(yè)名稱兒科學（神經專業(yè)）論文答辯日期2016年5月20日ThecrelationofCarbamazepinewithOccurrenceofElectricalStatusEpileptic

2、usduringSleepinBenignEpilepsywithCentrotempalSpikesAbstractsObjective:ToexplethecrelationofCarbamazepine(CBZ)withoccurrenceofElectricalStatusEpilepticusduringSleep(ESES)inBenignEpilepsywithCentrotempalSpikes(BECT).Method

3、s:Theclinicaldataof6casesofESESin219casesofBECTinourhospitalwereanalyzedretrospectively.Results：Theonsetageof219childrenrangedfrom4yearsto12years.therewere6casesofESESoccuramong123patientstakingCBZ(CBZgroup)Nopatienttrea

4、tedwithvalproatetopiramateshowedESESamong96patients(nonCBZgroup).TherewasasignificantdifferencebetweentheCBZgroupnonCBZgroup(p0.05).ThedurationofESESdisappearedofftheirEEGrangebetween36monthsafterdiscontinuationofCBZ.fiv

5、ecasesofESESof6occurassociatedwithCentrotempalspikesConclusion：CBZcaninduceESESinthetreatmentofBECTalthoughitrarelyhappen.ThereisacertaincrelationbetweenESEStheBECTwithspikewaveinRolicarea.Postgraduatestudent:HuangQikunD