藜蘆醛和3，4—二甲氧基苯乙醛的合成研究.pdf

1、東南大學(xué)碩士學(xué)位論文藜蘆醛和3，4—二甲氧基苯乙醛的合成研究姓名：賈樹香申請學(xué)位級別：碩士專業(yè)：應(yīng)用化學(xué)指導(dǎo)教師：王明亮20060407東南大學(xué)碩士學(xué)位論文AbstractVeratraldehyde，34dime!thoxybenzeneacetaldehydeanditsderivativesareimportantsyntheticflavourormedicinelintermediatesInthispapersyntheti

2、croutewithlowercostandsimpleroperationwasdesignedtothesynthesisofvemtraldehyde，34dimethoxybenzeneacetaldelayde，twoprotectproductswhichare4(2，2dimethoxyethyl)一1，2dimethoxybenzeneand2(3，4dimethoxybenzyl)1，3一dioxolaneandtwo

3、derivativeswhichare34dimethoxyphenylacetaldoximeandNmethyl3，4dimethoxyphenylamineTheprocessesarementioned∞follows：1)VeratraldehydeWaspreparedfrompyrocateeholbymethylationandvilsmeierreactionManyfactorsinfluencethereactio

4、nwerestudiedandthebetterconditionswgregotTheyieldiSabeve85％12dimethoxybenzenunreaetedWasrecoveredwithsolventNmethylformanilidecanalsoberecoveredintheformofNmethylphenylamine111eyieldhasincreased25％andthismethodhasapotent

5、ialapplicationinproduction2134DimethoxybenzeneacetaldehydewaspreparedfromveratraldehydebyDarzen’Scondensation，alkalinehvdrolysisanddecarboxylationthreesteps，thelawmaterialusedintheliterature2butylalcohol，potassium2butoxi

6、deand2butylehloroacetatearerespectivelyreplacedbymethan01sodiummethoxideandmethylchloroacetate，andmolarratioofthematerialsisfoundThetotalyieldiS583％SotheprocesscanbeUSedintheindustry3、Twoprotectsof34一dimethoxybenzeneaeet

7、aldehyde，4(2，2dimethoxyethyi)一1，2dimethoxybenzeneand2(3，4dimethoxybenzyl)一1，3dioxolanewerepreparedbycondensationwithmethanolandethaneI，2diol，theyieldwere810％and559％respectively2一(3，4一dimethoxybenzyl)l，3dioxolaneisnewcomp

8、ound4)Twoderivatives，34dimethoxyphenylacetaldoximeandNmethyl一3，4dimethoxyphenylamineweresynthesizedAndthelatterWaspreparedthroughcondensationwithmonomethylamine，reductionbycatalizedhydrogenationorsodiumborohydride，andthe