有機雙過氧釩化合物的合成及其與幾種小分子相互作用研究.pdf

1、廈門大學(xué)碩士學(xué)位論文有機雙過氧釩化合物的合成及其與幾種小分子相互作用研究姓名：黃婷申請學(xué)位級別：碩士專業(yè)：物理化學(xué)指導(dǎo)教師：陳忠20060501SynthesesofOrganicDiperOxoVanadatesandInteractionswithSomeSmallMoleculesTingHuangABSTRACTInthepasttwodecades，theinteractionsbetweenperoxovanadatesan

2、dorganicligandshaveattractedgreatinterestinbothchemistryandbiologyInthiswork，multinuclearNMR(1H，BC，14Nand51v)，multidimensional(DOSY1H_lHcosYand”C)Hcosy)，andvariabletemperatureNMRwereutilizedtostudytheaboveinteractionsyst

3、emsThroughthecombinationofthesemethods，structuresofallspeciesininteractionsystemswereobtainedandabetterunderstandingoftheexperimentalphenomenawasachievedThesestudiesshedsomelightontheessenceofthevanadium—containedenzymes

4、uchaschloroperoxidaseThemainconclusionsaresummarizedasfollows：1MultinuclearNMRmultidimensionalandvariabletemperatureNMRtechniqueswereusedtostudytheinteractionsbetweendiperoxovanadatesandsmallorganicmoleculessuchassubstit

5、utephenanthrolineandoxazoleTheirstereochemicalstructuresinsolutionwerediscussedaccordingtotheNMRsignalsoftheorganicligandsAll1Hand13CpeakswerecompletelyassignedandthepredominantinteractionpattemofthesecomplexesWaspropose

6、d2NMRstudyontheinteractionsbetweendiperoxovanadatesandhistidinelikeligandsshowsthatGlyHisandGlyHisGlycoordinatestovanadate(V)byits￡—NwhichisthesameasHis496intheactivesiteofchloroperoxidasefromthefungusCurvularMinaequalis