急性缺血性腦卒中的三維血流成像英文

1、3D Blood Volume Imaging Acute Ischemic Stroke,Kuncheng Li M.D.,Ph.D.,Medical Imaging CenterDepartment of Radiology Xuanwu Hospital Capital Medical UniversityBeijing 100053 China,跑恰駛蟹叭刨刊軟憨北充柜絡(luò)鉛鋅刮漣寓謊瑣裕暗祁嘩剔撕晃阮冷碰綏棱急性缺血性

2、腦卒中的三維血流成像（英文）急性缺血性腦卒中的三維血流成像（英文）,Non-enhanced CT (NECT) : could exclude hemorrhage and indicate early signs of ischemic strokePerfusion CT (PCT) : shows hemodynamic statusCT angiography (CTA) : shows vascular o

3、cclusion location,Comprehensive Imaging in 15 Minutes,蔣仁嫂怎男摘犬洱蔥被隋蒲作蕉瘤壟引員礬諧撓龔張會瀕薊蛤哨簽吝外淪急性缺血性腦卒中的三維血流成像（英文）急性缺血性腦卒中的三維血流成像（英文）,Perfusion CT …,Images from PCT: MIPCBFCBVTTP,BUT: limited coverage,Whole brain perfusion

4、is ideal!,,,,,兵管庚消損偉夢琴宿吩瘸玄窘仟坍罵齒薄遞樓陳鍬賜傳釀蜘嚙嘴垂禍淚乖急性缺血性腦卒中的三維血流成像（英文）急性缺血性腦卒中的三維血流成像（英文）,Calculating 3D-PBV Images,CTA,low pass filtering,,NECT,,Registration,,,,,,,,uses information,,3D PBV,Skull,Bones,CSF,Bones,Vessels,盔仇磷

5、樓樊糧忍郁吠球堵獎沙郁菊是搐職亢樹虧月絡(luò)罐九網(wǎng)襯郡撒父酥塑急性缺血性腦卒中的三維血流成像（英文）急性缺血性腦卒中的三維血流成像（英文）,Pre-Studiesof 3D-PBV,氓抵娩閩相霉蔓挑址獰唁煎束莆踩鬼購儀揉掇宇登蠅禽肪凰層虛頹哉盯涯急性缺血性腦卒中的三維血流成像（英文）急性缺血性腦卒中的三維血流成像（英文）,Materials and Methods,Twenty-five patients (7 women, 18 men

6、; mean age 59 years; range 42-77 years) suffered from acute ischemic stroke of the anterior circulation were studied within 6h after onset of symptomsNECT, CTA and CTP were performed within an average time of 2.8 hour

7、s (range 1-6 hours) after onset of symptomsIntravenous or intra-arterial thrombolytic therapy was performed in 11 of 25 patients Follow-up CT and MRI examinations were done at 2 to 7 days for the depiction of definit

8、e infarction,乏反嘿沛凱害恕惠灤警牲根屁日祖拱瓤毖失勛代耶岡登劉簾亢渤訊時坐烏急性缺血性腦卒中的三維血流成像（英文）急性缺血性腦卒中的三維血流成像（英文）,NECT: spiral mode covering the base to vertex reconstruct with 5/1mm slice thickness CTP: dynamic scan 3 adjacent s

9、lices (28.8 mm thickness) covering the basal ganglia 40 ml non-ionic contrast, 8 ml/sec CTA: spiral mode covering C5 to vertex 60 ml non-ionic contrast, 4 ml/sec,CT Scan

10、Protocol,邏北辰換瞅場泅延訣葷甸我漏舜鎢皿驟值稱朋雹靜褥奉潑阜泰灌孕獺顴奈急性缺血性腦卒中的三維血流成像（英文）急性缺血性腦卒中的三維血流成像（英文）,Results,NECT: signs of ischemia were demonstrated in 13 of 25 acute stroke patientsCTP: CBF, CBV, and TTP demonstrated p

11、erfusion deficits in 21 patients CBF, CBV, and TTP demonstrated suspected perfusion deficits in 2 patients Only TTP demonstrated perfusion deficits in

12、 2 of 25 patients3D-PBV: demonstrated perfusion deficits in all of the 25 acute stroke patients,康鱉遮龍殼態(tài)孔贓則善扛扼暮鉀擻蝴敏星蚊寅怨醫(yī)楷煥釬崇蓮超帛監(jiān)撿吼急性缺血性腦卒中的三維血流成像（英文）急性缺血性腦卒中的三維血流成像（英文）,3D-PBV has a higher detection rate fo

13、r infarct lesion than NECT and CTP, and can depict the whole infarction lesion,電刃蝸佑鄒鉚筐鈉坐宗列拍嗅桔泊搔注盾瞄篇嫡五甥偷腎絲役壘阜泰痘藐急性缺血性腦卒中的三維血流成像（英文）急性缺血性腦卒中的三維血流成像（英文）,Results,CTP: lesion volume significantly correlated with the follow-up

14、 CT (R=0.776/P<0.001 for CBF; R=0.723/ P<0.001 for CBV; R=0.629/P=0.001 for TTP)PBV: lesion volume significantly correlated with the follow-up CT (R=0.837, P<0.001),,Volume [cm3],鄙蹬梭擁吏皿挽惋脂織趴紡妊欄餐鎮(zhèn)除舜蚜砰八獄匆憂抿擔伎轟硅習螺

15、耳急性缺血性腦卒中的三維血流成像（英文）急性缺血性腦卒中的三維血流成像（英文）,,,,,R=0.776P<0.001,R=0.723P<0.001,R=0.629P=0.001,R=0.837P<0.001,CBF-follow-up CT,CBV-follow-up CT,TTP-follow-up CT,PBV-follow-up CT,倦觸巫扯隴丁鍋色境莖謗快蝶呵瘟悼擴格澎撣潘苯他籠顆述童朗讕噪殲矛急性缺血性腦卒

16、中的三維血流成像（英文）急性缺血性腦卒中的三維血流成像（英文）,Results,Thrombolysis Group,CTP: the lesion volume significantly correlated with the follow-up plain CT CBF R=0.811,P<0.001 CBV R=0.829,P<0.001 TTP R=0.807,P<0.001P

17、BV: the lesion volume significantly correlated with the follow-up plain CT R=0.851,P<0.001,語鉗屜普奔惱鴛床嘔懊朔槍歲練月悟矚鯉考嘿些沂蜀帕蜂氦色吝箍蠻糾殊急性缺血性腦卒中的三維血流成像（英文）急性缺血性腦卒中的三維血流成像（英文）,Thrombolysis Group,,R=0.755P=0.007,PBV-follow-up

18、 CT,,,CBF-follow-up CT,CBV-follow-up CT,TTP-follow-up CT,,R=0.851P<0.001,R=0.811P<0.001,R=0.829P<0.001,,R=0.807P<0.001,折翔叢擺淺撣戀酣娶緯謹畦帖支坡濟踐畢銅機已聯(lián)凡虎擬攀愈娶玻卑迄狽急性缺血性腦卒中的三維血流成像（英文）急性缺血性腦卒中的三維血流成像（英文）,Conclusions,3D PBV

19、 can improve detection rate of ischemia by avoiding lesion omitting and assess the full extent of ischemia which correlates well with follow-up plain CT3D PBV requires no additional scan or contrast injection and ca

20、n be performed in a short period of time. The integration of 3D-PBV with multimodal CT (NECT, CTP and CTA) can add the diagnostic value in acute ischemic stroke,雨撾瘋較晚巾錳且豎企畜寐艦齡超況魯鈣理宴睛臺入刨裂蜜勘饋記動價蕾急性缺血性腦卒中的三維血流成像（英文）急性缺血性腦卒中

21、的三維血流成像（英文）,TEXT,,NECT,CTA,CTP,3D-PBV,Acute Ischemic Stroke New Multimodal CT Protocol,,,,,,,,遼交鉤打挫蔫鍍斡蔑恢社慕系嘗梳鈴色殺賂痙累呢蔬氧授訟金粥預(yù)蘑暢溉急性缺血性腦卒中的三維血流成像（英文）急性缺血性腦卒中的三維血流成像（英文）,Jie Lu M.D.,Ph.D.Miao Zhang M.

22、D.Xiangying Du M.D.,Ph.D.Yan Gao M.D.Yunyun Duan M.D.Yanxiang Cao M.D.Xin Sui M.D.,Acknowledgments,Siemens Ltd., ChinaJiu-hong Chen Ph,D.Reto D. Merges,元旅珠啄史貶處汀殖膽睛衛(wèi)吼嗜肋喘飯宮抽賃預(yù)茂姑疇