血清總IgE抗體及特應(yīng)性過敏原與兒童抽動障礙的臨床研究.pdf

1、軍醫(yī)進修學(xué)院解放軍總醫(yī)院碩士學(xué)位論文血清總IgE抗體及特應(yīng)性過敏原與兒童抽動障礙的臨床研究姓名：鞠俊申請學(xué)位級別：碩士專業(yè)：兒科學(xué)指導(dǎo)教師：鄒麗萍20120603軍醫(yī)進修學(xué)院碩士學(xué)位論文ClinicalStudyontheTicDisordersandSerumTotalIgEandAllergenspecificIgEAbstractObjective：TicDisorders(TD)isaconditionofthenervouss

2、ystemanditsetiologyiscurrentlyunknownThus，thestudyaimedtoinvestigatetherelationshipbetweenallergicsensitizationandTDMethod：Acase—controlexperimentwasconductedThetotalandallergenspecificimmunoglobulin(Ig)E(slgE)levelsinth

3、eserumsamplesof72childrenwithTD(TDgroup)and50childrenwithallergicdiseases(controlgroup)weremeasuredinalaboratoryafterhistorytakingbyclinicaldoctorThreemillilitersofveinbloodwascollectedfromeachchild，andthetotalIgEaswella

4、sinhalantandfoodslgElevelsintheserumweremeasuredusingEUROLINEAtopy(China3)(IgE)fromEUROIMMUNMedizinischeLabordiagnostikaAG(China)MoreoverthechildrenwereevaluatedforcomorbidityofallergicdiseasesThedatawasanalysedwithstati

5、sticallyResults：TheageofTDchildrenwas3～15yearsoldwithameanageof(888275)yearsoldTheboywasapparentlymorethangirlTheTDandcontrolgroupshad61and44caseswithpositivetotalIgEresults，respectivelyThepositiverateintheTDgroupwas8472

6、％，whereasthatofthecontrolgroupwas88％MoreovertheTDgrouphad50caseswithpositiveslgE，withapositiverateof6944％，whereasthecontrolgrouphad37cases，withapositiverateof74％ThetotalIgEandslgEresultsofthetwogroupshadnosignificantdiff

7、erencesTheallergenscommoninTDgroupwerehousedust，woodcombination(willowpoplarandelm)，dustmites(DermatophagoidespteronyssinusandDermatophagoidesculinae)，fleshwaterfish(Salmosalarbass，Cyprinuscarpio)，andmilk／chocolatemixThe

8、commonallergensinTDsimilartothatintheADgroupComparedwithpositiverateofmorethan2allergensspecificIgE，nostatisticalsignificancewasfound(P005)TherankdistributionsofthetotalIgEresultsinTDgrouphadnothingtodowiththecourseofthe