玉米素以及幾個(gè)精細(xì)化工中間體的合成與工藝研究.pdf

1、山西大學(xué)碩士學(xué)位論文玉米素以及幾個(gè)精細(xì)化工中間體的合成與工藝研究姓名：李歆申請(qǐng)學(xué)位級(jí)別：碩士專(zhuān)業(yè)：有機(jī)化學(xué)指導(dǎo)教師：夏熾中郭煒20040601摘要AbstractThefirstpartAsoneofphytohormones，transzeatinisthefirstoneofcytokininsthatisseparatedfromplantItisbasicmaterialthatplantsneedinthecourseofgr

2、owthInallofcytokinins，thetramszeatinisthemostactiveBecausethereislittlezeatinintheplant，itsdifficulttoabstractitfromnaturetosupplythedemandsSoitisurgenttoexploitasyntheticmethodforcurrentdemandsSofartherearedozensofmetho

3、dstosynthesizeliens—zeatin，butnoneofwhichiseffectivewithgoodyieldandpurityInthisworkWeselectedtwosyntheticstrategiesbasedonthesurveyofthelitemturesAftercarefulstudies，weobtainedegoodsyntheticmethod，withwhichkgscaleproduc

4、tCanbeprovidedwith99％purityThesoeondpartNowdays，thetrendofdevelopmentofchemicalindustryintheworldisshiftingtofinechemistryandthestructureofchemicalindustryischangingInthepastseveraldecades，thereisquietgreatadvancementine

5、veryfeldoffinechemistryHowevertheprogressin0111“countryisrelativelyslowSoitisveryimportanttostudyappliedchemistrywhichcanmakescienceandtechnologyintoproductivitySubstituteddiphenoxideethaneisusedasadditiveinthecourseofsy

6、nthesizingmacromoleculematerialSincetherearesomedisadvantagesinformermethodsuchaspooryieldsandcomplexmanipulationgreatdemandsattheinternationalmarketCannotbesatisfiedentirelyBasedontheoryoftheneighboringgroupparticipatin

7、gandtheoryofphaSetransfercatalysis，WehaveimprovedtheyieldandsimplifiedoparetionoTrifluoromethylbenzoylchloride，animportantmedicalintermediate，havebeensynthesizedwithotrifluoromethylchiombenzeneasthestartingmaterialthroug

8、hthleestepreactionsincludingthepreparationofGdgnardreagentthesubsequemadditionwithC02，andthecarbonylchloridereactionwithSOCl2SeveralimprovementshavebeendoneinthispaperaSfollows：(I)screeningouttheoptimalassistantreagemCH3

9、CH2Br；(II)replacingdryicewithC02；(III)solvingtheproblemoftherecycleofTHF；(IV)facilitatingthepreparationofotrifluommethylbenzoylchlorideWiththeaboveimprowments，thesyntheticconditionsofotrifluommethylbenzoylchloridea地veryf