直接曼尼奇反應(yīng)合成新型二茂鐵衍生物.pdf

1、蘭州大學(xué)碩士學(xué)位論文直接曼尼奇反應(yīng)合成新型二茂鐵衍生物姓名：王小軍申請(qǐng)學(xué)位級(jí)別：碩士專(zhuān)業(yè)：有機(jī)化學(xué)指導(dǎo)教師：陳保華20050501⑧蘭州大掌2005屆碩士掌位論王小軍AbstractThisthesisfocusesonthestudyofthenewlydevelopeddirectMannichreactiontosynthesisofnovelferrocenylderivativesThisthesismainlyconsist

2、softhefollowingtwopartsThefirstpartisreviewswhichcontainsthreechaptersThefirstchapterbrieflyintroducesthedevelopmentofOrganmetallicChemistryTheOrganmetaMcChemistryisoneofthefootstoneofmodemsynthesischemistryAndinthischap

3、teralsobrieflyintroducethenewlydevelopedOrganmetallicChemistryDirectedtowardsOrganicSynthesis(OMCOS)，ThesecondchapterintroducestheapplicationsandthedevelopmentofferroceneanditsderivativesFortheparticularityofitsstructure

4、andthestabilityofchemicalpropertytheferroceneanditsderivativeshaveapromisingapplicationforeground，ThethirdchapterfocusesOiltheapplicationsandthedevelopmentofMannichreactionThisreactiontypeisunusuallyvaluableandhasaremark

5、ablywiderangeofapplicationsThismeans，morespecificallythatitstartsfromcheapstartingmaterialsandprovideskeybuildingblocksforpharmaceuticalsandnaturalproductsinaninexpensivemannerThischapteralsointroducesthenewlydevelopeddi

6、rectMannichreaction，whichaccordwith“atomeconomy”ThesecondpartisthestudyofdirectMannichreactiontosynthesisofnovelferrocenylderivativesThisthesisuseferrocenccarboxaldehyde，acetophenoneandaseriesofamide，adoptingdirectMannic

7、hreactioninone—pot，toformnovelferrocenylMarmichbasesThereage21productsandalloftheirbasicpropertiesarecharactersby1HNMR，”CNMR，MSThisprocessoffersconsiderablesynthesisadvantagesintermsofmildreactionconditionandsimplicityof