VC、VE預處理對犬氟烷吸入麻醉的影響.pdf

1、中國農業(yè)大學碩士學位論文VC、VE預處理對犬氟烷吸入麻醉的影響姓名：成安慰申請學位級別：碩士專業(yè)：臨床獸醫(yī)學指導教師：湯小朋潘慶山20070601AbstractHalothane鋤producesfreerediacalsduringbioreansformationOccasionallythesef沁eradicalsmaycau∞liverinjuryVitaminCandvitaminEmay—o‘ectcellularlip

2、idsandlipoproteinsagmnstoxidativedamagebyfreeradicalsThisstudywasinvestigatedtheeffectsofvitaminCandvitaminEOnthedogsanesthetizedwithhalothaneAlldogswererandomlydividedintothreegroupsThefistgroupwasusedasacontrol，notgive

3、nvitaminCorvitamineE，thesecondgroupwaspretreatedvitaminCbeforehalothaneanesthetizedthethirdgroupwaspretreatedvitaminEbeforehalothaneanesthetizedTherewere6healthadultminimalmodeldogsineverygroupAllthedogswereanesthetizedb

4、，rhalothanefor3hVenousbloodsampleswerecollectedforliverenzymesandotherbiochemicalparameterstestsonedaysbeforeanesthetized，and24h，and3，7and14daysrespectivelyafteranesthetizedTheresultswereshownasfollows：heartratebloodpres

5、sureandtemperatureWCI“estatisticallyaffectedduringtheanesthesiawithhalothaneTheactivitesofALl“andASTwerenotsignificantlyincreasedaftertheanesthesiainthecontrol，buttheactivityofGGTWasincreasedbetween3and7daysafteranesthes

6、iatheactivityofALPWassignificantlyincreasedbetween24hand7claysafteranesthesiaandtheactivityofLDHWitSsignigicantlyincreasedinthepdayafteranesthesiaTheactivitiesofALTASTGGTandLDHwerenotsignificantlyincreasedafteranesthesia

7、inthesecondgroupandthethirdgroupTheactivityofALPwassignificantlyincreasedbetween24hand7dayinthethirdgroup，butnotinthesecondgroupallthetimeafteranesthesiaComparedwiththecontrol，theactivitiesofALPandLDHwe∞statisticallyaffe

8、ctedinthesecondgrouptheactivitiesofALPWasnotstatisticallyaffectedbuttheirchangeswereinthetendenceofdecreasioninthethirdgroupTheresultsofstudywereindicatedthatvitaminCpretreatedinanesthesiawithhalothanemayplayanimportantr