EEG偶極子在癲癇定位診斷中的應(yīng)用.pdf

1、9碉158jr炎一：!墮衛(wèi)jj167級：冀——生一UDo^m——學％Q坐j東南碩女學大學位論文EEG偶極子在癲癇定位診斷中的應(yīng)用研究牛舛名塑墮重導師姓名揚丟墮麴撞肯㈠綴Z0匡塋亟一J、W：l。監(jiān)幸i班、處型蘭f麴堡多t登塋!論文提交㈠圳!避j笙6最!!：旦一》文答辯[。刪!塑墨生鰻雖!!呂彳’位授J：單位—童一直杰蘭學位授弘r1期!魚旦!笙旦一旦答辯蛋員會I—i要房童一，—評閑人重墮一HG偶極了訂搗痛定位診斷中的應(yīng)用Studyofthe

2、dipolesourcelocalizationforpre—operatiVelocalizationoftheepileptogenicdischargesinpaticntswithiⅡtractableepilepsyGraduate：guoxiaoyuanSuperVisor：yangtianmingAbstractobjectivc：Inorder10evalualetheefkctivenessofpresurgicald

3、ipoleanalysisofintenctalandseizu陀onsetphasespikesasanoninvasivetechniqucforthedete丌T1inationofepilcptogcnjcarea，wecomparedtheresuhsofthismethodwiththoseofelectrocorticography(ECoG)localizationandMR】Methods：25consecutivep

4、alientswhohadVEMfbrpresurgicaleValuationofmedicaIlyrefractorypanialepilepsyweresc陀enedA11patientshadfocalIntericlalspikeswhichrecordedbytheoxfordsystem16aretemporallobeepilepsy，7areoccipitallobeepilepsy，and2areunc】assi矗e

5、dInterictala11dseizureonsetphasespikeswe陀analysisedbyBESAsoftware，whichprovidedmany“ndsofanalysjsmethods，suchasSequen“aldipolentting、initial6ttingofthespikepeak、regionalsource(4ofthem10sttheepilepticseizures’sEEGintheobs

6、crvation)Difkrentmethodsofdipolesourcelocalizationwerecomparedtoexploretherelationshjpoftheonsetregionandseizurere西onA11sampleswereexaminedinhist0109yandMRIresultswereconsjderedtojnvestigatethefactorsjn門uencingprognosisR

7、esuIts：Thed引krenceindip01e10ctionsbetweentheindiVidualandgrand—aVerageddatasetswasnotstatisticallysignincant11hemethodofdipolesourcelocalizationwasbetterthanroutineEEGjnspace—timediscriminationTheresultsusingsinglespikeo

8、raVeragedspikeanalysismethodshadnoobViouslyd訓了色renceHoweVer，averagedspikeanalysiswasthemoreef詫ctiVemethodstoobtainthebackgroundrh”hmic1naddition，MRlresultsindicatedthecorrelationofhippocampussclerosjsandepileptogenic1esi

9、n，whichcon^rmedbypostoperationpath0109yConclusion：TheanalysistoEEGshouldbeonthebasisofneuroanatomyandelectrophysjologyknowledgeDipoIesourcelocalizationmethodwasbetterthanroutineEEGinspace—timediscrimination1owever，becaus