3.0tmri動態(tài)增強(qiáng)掃描、表觀擴(kuò)散系數(shù)及磁共振波譜成像在乳腺病變中的診斷價值

1、山西醫(yī)科大學(xué)碩士學(xué)位論文3.0T MRI動態(tài)增強(qiáng)掃描、表觀擴(kuò)散系數(shù)及磁共振波譜成像在乳腺病變中的診斷價值姓名：程潔申請學(xué)位級別：碩士專業(yè)：影像醫(yī)學(xué)與核醫(yī)學(xué)指導(dǎo)教師：張輝2011-03-10山西醫(yī)科大學(xué)碩士學(xué)位論文 山西醫(yī)科大學(xué)碩士學(xué)位論文 Diagnostic Value of 3.0T DCE-MRI, Apparent Diffusion Coefficient and Magnetic Resonance Spectrosco

2、py in Breast Diseases Abstrat Objective: To approach the value of dynamic contrast-enhanced breast magnetic resonance scan (DCE-MRI) morphology, time-intensity curves, apparent diffusion coefficient (ADC value) and magne

3、tic resonance spectroscopy(MRS) in the diagnosis breast diseases, to provide a richer, more valuable information for clinical preoperative diagnosis of breast diseases. Materials and Methods: Collected the doctor suspect

4、ed breast lesions at our hospital needing further diagnosed 28 patients from July 2010 to March 2011 period, A total of 35 lesions,all are women,35 to 72-year-old, average 48-year-old. Preoperative magnetic resonance sc

5、an of conventional, diffusion-weighted imaging , dynamic contrast-enhanced scans and magnetic resonance spectroscopy, postoperative patients with pathologically confirmed, including 9 benign cases of 16 lesions, maximal

6、diameter of lesions 0.8～7.1cm,average 3.2cm.19malignant cases of 19 lesions, maximal diameter of lesions 0.9～5.6cm, average 2.8cm .Analysis of breast DCE-MRI morphological performance (including the tumor shape and edge)

7、, DCE-MRI time-intensity curves, the measured ADC values and MRS in the identification of benign and malignant breast lesions. Results: ①After dynamic contrast-enhanced,morphology of the sensitivity of diagnosis of breas

8、t cancer is 73.7%(14/19), specificity is 93.8%(15/16),accuracy is 82.9%(29/35);②Time-intensity curves of the sensitivity of diagnosis of breast cancer is 89.5%(17/19),specificity is 68.8%(11/16),accuracy is 80.0%(28/35);

9、③Apparent diffusion coefficient (ADC value) of the sensitivity of diagnosis of breast cancer is 94.7%(18/19),specificity is 81.3%(13/16),accuracy is 88.6%(31/35); Magnetic resonance spectroscopy(MRS) ④of diagnosis of bre

10、ast cancer is 63.2%(12/19),specificity is 87.5%(14/16),accuracy is 74.3%(26/35); Combining morphology ⑤and ADC values of the sensitivity of diagnosis of breast cancer is 98.6%,specificity is 76.2%,accuracy is 88.6%; Com

11、bining TIC and MRS of the sensitivity of diagnosis of breast ⑥cancer is 56.6%,specificity is 96.1%,accuracy is 74.3%. Conclusion: DCE ① -MRI of the breast in the differential diagnosis of benign and malignant disease,i

12、rregular shape,edge blur, blurred boundaries,filling-type ring enhancement,Ⅲ-type curve is typical of imaging findings of breast cancer;The shape is round or oval,sharp and smooth edges,homogeneous enhancement,Ⅰ-type cur

13、ve of benign breast lesions diagnosis. ②DWI with short time and without enhancement in breast diagnosis of benign and malignant lesions of the ADC threshold value was 1.222×10-3mm2/s,ADC ＜ 1.222×10-3mm2/s was d