三陰性與非三陰性乳腺癌X線(xiàn)表現(xiàn)的對(duì)比研究.pdf_第1頁(yè)
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1、青島大學(xué)碩士學(xué)位論文三陰性與非三陰性乳腺癌X線(xiàn)表現(xiàn)的對(duì)比研究姓名:崔春曉申請(qǐng)學(xué)位級(jí)別:碩士專(zhuān)業(yè):影像醫(yī)學(xué)與核醫(yī)學(xué)指導(dǎo)教師:林青20120602Comparisonofmammographybetweentriplenon—triplenegativebreastcancerAbstract㈨v呲2㈣08㈣740㈣91negativeandobjectiveTocomparativeanalysethemammograpllicfindi

2、ngsbetween“triplenegative”breastcancer(thatiSestrogenreceptor【ER】negative,progesteronereceptor【PRlnegative,andhumanepidermalgrowthfactorreceptor2【HER2】negative,TNBClandnontriplenegativebreastcancerandevaluatetherelations

3、hipsofimmunohistochemologicreceptorstatusandmammographicfindingsMaterialsandMethodsW宅identifiedl102womenwhohadbeendiagnosedwithprimarybreastcancerbetweenJanuary2009andDecember2011atasignalhospitalandwhohadundergonemammog

4、raphyatinitialdiagnosisTherearel74casesofTNBC,97casesofER十/PR/HER2,65casesofER卜/PR/HER2,183casesofER/PR/HER2and583casesofER伊R“HEI匕一breastcancerA11ofthelesionswereconfirmedbyhistologicalexaminationsWreretrospectivelyevalu

5、ated也evisibilitymorphologydistributionandsizeofthelesion(massesandcalcifications)andbreastdensityonmammographyof1NBCandtocomparewiththoseofnonTNBCSWealSeviewedtheageandpathologictypeofTNBCandnon—TNBCsResults①Themeanageof

6、1NBCandnonTNBCsWassiganificantlydifferent儼3877,PO05),andthemeanageofTNBC(51992【3287])WasolderthanthatofER伊R/HEI也(483士89[2668])(尸=0007)②InfiltratingductalcarcinomaWasthemainpathologictypeofallgroups,andbasal—likebreastcan

7、ceraccountedfor477%(83/174)of耶NBCwhileonlylornocaseinnon一11呵BCgroups③TNBCweremorefrequentlyassociatedwithmerelyamass(95/1501633%】),roundorovalwithindistinctmarginthannonTNBCs∥=81467,PO01),andthemeandiameterofthemassofTNB

8、C(239341159mm)WaslargerthanthoseofnonTNBCs(辟4619,P=0001)1NBCwerelessfrequentlyassociated、vithmicrocalcifications(9/150【6O%】)thannonⅢBCs∥=31997,POO1)④MammographicdensitywassignificantlydifferentwiththatofER竹,PR/HEI也breast

9、cancer(2/=9381,P=0025)ConclusionThemammographicfeaturesofTNBCthatlesionsshowmerelyamass,roundorovalwithindistinctmargins1agerinsizeandlessassociatedwithmicrocalcificationsmightbeusefulindiagnosingtriplenegativebreastcanc

10、erThemeanageofTNBCis52yearsoldandthemainhistopathologicfindingiSinfiltratingductalcarcinomawithahighproportionofbasallikebreastcancerPostgraduate:CuiChunxiao(Medicalimaging)DirectedbyProfLinQingKeywords=triplenegativebre

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