L-Plastin在子宮內膜異位癥患者在位內膜及異位病灶中的表達及意義.pdf

1、中國醫(yī)科大學碩士學位論文LPlastin在子宮內膜異位癥患者在位內膜及異位病灶中的表達及意義姓名：張弛遠申請學位級別：碩士專業(yè)：婦產科學指導教師：王丹波20090301英文論著摘要ExuandSignificamofLPl：lstin‘thExpressionancanceLvlastminthe●EutopicEndometriumandEctopicFociofEndometriosisObjectiveToexploretheca

2、ndidategeneanditsfunctionintheeutopicendometriumofendometriosis；bythemeasurementoftheexpressionofL—plastininendometrium，investigateitsfunctioninthedevelopmemandprogressionofendometriosis，supplyprooffortheearlydiagnosisof

3、endometriosisMethodsTheeutopicendometriaandectopieendometriaof50cases，whichwerepathologicallyprovedendometriosis，werechosen嬲experimentalgroup，andtheeutopicendometriaof13c2LseswithoutendometriosisascontrolgroupTheexpressi

4、onofL—plastinmRNAwasdetectedbyReverseTranscriptionPolymeraseChainReactionandthecorrelationbetweenLplastinexpressionlevelineutopicendometriaandtheseverityofendometriosiswereanalyzed。ResultsTheexpressionlevelofL—plastinint

5、heeutopieendometriaandtheectopicendometriaofpatientsweregreaterthanthoseincontrolgroup口o05)，andtheexpressionlevelofL—plastinintheectopicendometriaweregreaterthanthoseintheeutopicendometriaofpatients(P005)ConclusionTheunu

6、suallyelevatedlevelofL—plastinmayplayanimportantroleinthedevelopmemandprogressionofendometriosis，andLplastinmaybeoneofthespecialtargetgenesofendometriosisKevwordsendometriosis；L—plastin；RTPCR；eutopicendometrium；ectopicen