三奇注射液對肝癌小鼠IFN-γ和TNF-α影響的實驗研究.pdf

1、yt405759專業(yè)代碼——衛(wèi)Ⅲ鯉學—業(yè)盟墊iL陜西中醫(yī)學院ShaanfiUnIⅧicvofChinBeMedicine碩士學位論文三壹些盟亟型壁塞4二盟!塑]塑!豎理影響的實驗研究學位申請專業(yè)名申請學位類指導教師姓論文提交日人稱型名任末峰中西醫(yī)結臺臨床腫癌臨庥醫(yī)學碰士專業(yè)學位孔平幸教授期2008年4月ToStudytheImprovementFunctionofSanqiInjectiontoH22HepatiaoftheLeveIo

2、fIFN一吖andTNF一詛inH22HepaticaTumorCeIICytopIasmAbstractObjectiveTostudytheresistantfunctionofSQtoH22hepatica，influencetotheweight，therateofrestrainingtumor，theindexofimuneorgans(thymus，spleen)，thelevelofIFNlandTNF—ainH船hep

3、aticatumorcellcytoplasm’MethodsH盟hepaticacellsweretransplantedsubcutaneouslytoICRmicewithrightmaxillaryonthesterilizedworktabable，thenextdayaftermakingmodel，miceweredividedrandomlyinto4groupsWithcompleterandomizing：thesa

4、linegroup(NS90mg／kg，fromthefirstdaytothefourteenthday)，theSQgroup(109／kg，fromthefirstdaytothefourteenthday)，theHCPTgroup(2mg／kg，fromthefirstdaytofourthday)，theSQandHCPTgroup(SQlOg／kg，fromthefirstdaytothefourteenthday；HCP

5、T2mg／kg，fromthefirstdaytothefourthday)，observingthegenerallivingconditionsofeachmouse，measuringtheweightofeachgroupmiceeveryday，killingmicebySeveringthejugulartoobstainthymus，spleen，transplantingtumor，measuringtheweighto

6、fthembytheanalyticalbalance，drawingtheweightcurve，calculatingtheindexofimmuneorgans(thymus，spleen)andtheinhibitionrateontumor，whilefixingthetumorbygroups，examiningthelevelofIFNlandTNF一0【innz2hepaticatumorcellcytoplasmRes

7、ultsComparedwiththesalinegroup，SQcanincreasetheweightofmice，enhancetheimmuneorgans(thymus，spleen)index(PO05)SOhasanti—tumoreffect(PO01)，canincreasethelevelofIFNlandTNF一0【inH22hepaticatumorcellcytoplasm(P001)Comparedwitht