[雙語翻譯]---外文翻譯--卵巢癌在懷孕期間的管理指南（原文）

1、ReviewGuidelines for the management of ovarian cancer during pregnancyHenri Marret a,1,*, Catherine Lhomme ´ b,1, Fabrice Lecuru c,1, Michel Canis d,1, Jean Le ´ve `que e,1, Francois Golfier f,1, Philippe Moric

2、e b,1a Centre Hospitalier Regionale et Universitaire de Tours, Ho ?pital Bretonneau, Tours 37044 ce ´dex 1, France b Institut Gustave Roussy, 39 rue Camille Desmoulins, 94805 Villejuif, France c Hopital Europe ´

3、;en Gorges Pompidou 20, rue Leblanc 75 Paris 15e `me, France d Hotel Dieu CHU bd Le ´on Malfreyt, 63058 Clermont Ferrand, France e Centre Hospitalier Universitaire de Rennes 16 bd de Bulgarie, 35200 Rennes, France f

4、 Centre Hospitalier Lyon Sud: Chemin du Grand Revoyet - 69495 Pierre Be ´nite, FranceContents1. Preliminary. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

5、. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 192. Diagnosis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

6、 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 193. Management . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

7、 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 193.1. Management of epithelial invasive tumours . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

8、. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 193.2. Management of non-epithelial malignant tumours. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

9、 . . . . . . . . . . . . . . . . . 204. Conclusion . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

10、 . . . . . . . . . . . . . . . . . . 20References . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

11、. . . . . . . . . . . . . . . . . . 20European Journal of Obstetrics however,they should be considered advisory and should not replace specific interdisciplinary consultation withspecialists in maternal–fetal medicine,

12、gynecologic oncology and pediatrics, as well as imaging andpathology, as needed.Second level ultrasound including Doppler is needed. MRI is not often necessary, and CA 125 is of lowcontribution. We suggest surgery be per

13、formed after 15 weeks gestation for ovarian masses which (1)persist into the second trimester, (2) are greater than 5–10 cm in diameter, or (3) have solid or mixedsolid and cystic ultrasound characteristics. During the a

14、ntepartum period surgical staging and debulking,unilateral salpingo-oophorectomy on the side with the tumour, peritoneal cytology and exploration arenecessary. Women found to have advanced stage epithelial ovarian cancer

15、 should consider havingcompletion of the debulking of the reproductive organs at the conclusion of the pregnancy. Ifchemotherapy is indicated, we recommend delaying administration, if possible, until after the deliveryor

16、 at least after 20 weeks in order to minimize the potential fetal toxicity.? 2009 Elsevier Ireland Ltd. All rights reserved.* Corresponding author at: Tours University Hospital, Ho ?pital Bretonneau, Department of Gynaec

17、ology and Obstetrics, Foetal Medicine, Medicine and ReproductiveBiology, Tours 37044 cedex 1, France. Tel.: +33 47 47 47 41; fax: +33 (0)2 47 47 92 73.E-mail addresses: marret@med.univ-tours.fr, h.marret@chu-tours.fr (H.

18、 Marret).1 On behalf of the French Working Group on Gynecological Cancers in Pregnancy SFOG (Socie ´te ´ Franc ¸aise d’Oncologie Gyne `cologique), SFCP (Socie ´te ´ Franc ¸aise de ChirurgieP

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