h.pylori感染與不同亞型功能性消化不良治療效果的關(guān)系

1、華中科技大學(xué)碩士學(xué)位論文H.pylori感染與不同亞型功能性消化不良治療效果的關(guān)系姓名：陳穎申請學(xué)位級別：碩士專業(yè)：內(nèi)科學(xué)（消化病學(xué)）指導(dǎo)教師：徐三平2010-05華 中 科 技 大 學(xué) 碩 士 學(xué) 位 論 文華 中 科 技 大 學(xué) 碩 士 學(xué) 位 論 文 2結(jié)論 結(jié)論： 以 PDS 為主要癥狀伴有 H. pylori 感染的 FD 患者， 根除治療或常規(guī)治療在短期內(nèi)均可顯著改善癥狀， 且常規(guī)治療顯示出更好的癥狀緩解效果。 但對于以 E

2、PS 為主要癥狀伴有 H. pylori 感染的 FD 患者，根除治療有利于短期內(nèi)癥狀改善。 關(guān)鍵詞 關(guān)鍵詞：功能性消化不良，H. pylori 感染，上腹痛綜合征，餐后不適綜合征 The relationship between H. Pylori infection and improvement of different subtypes of functional dyspepsia Abstract BACKGROUND：Fu

3、nctional Dyspepsia（FD）is a highly symptom complex that may be subdivided into postprandial distress syndrome(PDS) and epigastric pain syndrome(EPS) according to the Rome III Criteria. The relationship between Helicobacte

4、r pylori (H. pylori) infection and FD is uncertain. The FD patients with H. pylori infection need to eradicate H. pylori or not, whether eradication of H. pylori would relieve the symptoms in dyspepsia and whether this i

5、mprovement is associated with the different subtypes of FD remains controversial. AIM: To inquire the drug therapeutic effection on PDS and EPS of patients with FD. METHODS: seventy-seven patients with documented PDS an

6、d EPS based on Rome III Criteria of FD were enrolled in the study. The patients with H. pylori infection receiving gastroendoscopy were randomly allocated into two groups: eradication group and non-eradication group. Era

7、dication group were with anti-H. pylori triple therapy (Esomeprazole 20 mg bid, clarithromycin 500 mg bid, amoxil 1.0g bid), for 10 days, and then treated with Domperidone 10mg tid (PDS group) or Talcid 1.0g tid (EPS gro

8、up) , for 4 days. Non-eradication group and H. pylori non-infection group were treated with Domperidone 10mg tid (PDS group) or Talcid 1.0g tid (EPS group) ，for 14 days. 14C-Urea Breath Test (14C-UBT) was taken in the de