腦力蘇飲液對腎虛痰瘀型血管性癡呆的臨床療效評價及小鼠腦組織SOD等的影響.pdf

1、學(xué)位論文腦力蘇飲液對腎虛痰瘀型血管性癡呆的臨床療效評價及小鼠腦組織SOD等的影響ClinicalevaluationontheTherapeuticEffectofNaolisuoralnquidtreattheShenXBtanyusyndromeforvasculardementiaandtheeffectofVDmice’SbraintissuecontentofSOD，etal張曉雅申請學(xué)位級別：亟專業(yè)名稱：主醫(yī)囪型堂論文提交時

2、間：2Q12生壘且論文答辯時間：2Q12生5月二。一二年四月成都中醫(yī)藥大學(xué)碩士學(xué)位論文AbstractObjective：ClinicalevaluationonthetherapeuticeffectofNaolisutreatthevasculardementiaandexplorethemechanismofNaolisucapsulebytheexperimentalstudyofvasculardementiamodelinm

3、iceMethods：Clinicalevaluation：Collects30examplestOconformtotheVDresearchstandardpatient，dividesintothetreatmentgroupandthecontrolgroupeach15examplesobservationstochasticallyThecontrolgrouptakesorallyisHyderginepiece，thet

4、reatmentgrouptakesorallytheHyderginepieceandNaolisucapsule，Treatmentfor3monthsFuzzycomprehensiveevaluationofthepatientsCognitiveabilitydailylivingabilityandTCMsyndromes，andStatisticalanalysisofthesafetyindexExperimentals

5、tudy：Usestiesupthemousetwo—sidedarteriacarotiscommunisanteriortOblockthebloodstream，thepreparationrepeatedlyrepeatedlyischemiapoursintothemodelagain，aftermakingthemoldsucceeds，dividesintosham—operatedgroup，modelgroup，Hyd

6、erginegroup，highdoseofNaolisucapsulegroupandlowdoseofNaolisucapsulegroup，thelaterthreegroupsofthetreatmentgroupDetectionthemice’SbraintissuecontentofSODandMDAafteradministered15daysResults：Clinicalevaluation：Theefficacyo

7、fcognitiveability：thetotaleffectivenessoftreatmentgroupis80％，thecontrolgroupis53％，thetwogroupshavesignificantdifference(p005)TheefficacyofTCMsyndromes：thetotaleffectivenessoftreatmentgroupis73％，thecontrolgroupis70％，thetw

8、ogroupsdon’thavesignificantdifference(p005)ThethreeindicatorsusingfuzzycomprehensiveevaluationshowthattreatmentgroupbatterthanthecontrolgroupExperimentalstud)r：TheSODofmice”Sbraintissueisincreased(p005)，theMDAofmice”Sbra

9、intissueisdecreased(p005)ThelowdoseofNaolisucapsulegroupisthemostobviousConclusion：NaolisucapsulehasagoodeffectinVDpatientstheSODactivityofmice’SbraintissueisincreasedanddecreasingtheMDAcontentThecapsulehassomefunctionto

10、protectneuronsinbraincellswhichhasvalueinthefutureclinicaltreatmentKeywords：Naolisuoralliquid；VascularDementia；”ShenXUtanyu”syndrome：Curativeeffectappraisal：Cognitiveability：dailylivingability：TCMsyndromes；Thetotaleffect