針刺對家兔坐骨神經(jīng)損傷修復(fù)中Nogo-A蛋白和MAG的影響.pdf

1、陜西中醫(yī)學(xué)院碩士學(xué)位論文針刺對家兔坐骨神經(jīng)損傷修復(fù)中NogoA蛋白和MAG的影響姓名：李佩佩申請學(xué)位級別：碩士專業(yè)：針灸推拿學(xué)指導(dǎo)教師：王瑞輝20100401TheExperimentalStudyontheEffectoftheContentofNogoAproteinMAGinRabbit’sSciaticNerveInjuryRepairmentbyAcupuncturetreatmentAbstractTheExperiment

2、alStudyontheEffectoftheContentofNogoAproteinMAGinRabbit’sSciaticNerveInjuryRepairmentbyAcupuncturetreatmentAbstractObjective:Toobservethetherapeuticeffectoftreatingperipheralnerveinjurywithacupunctureprovidenewtheeticalb

3、asisfclinicbyexperimentalresearchofNogoAproteinmyelinassociatedglycoprotein(MAG)aftersciaticnerveinjury(SNI)inrabbits.Methods::48healthyadultrabbitswereromlydividedinto3groups:blankcontrolgroupmodelcontrolgroupacupunctur

4、etreatmentgroup.Exceptblankcontrolgrouptherightsciaticnerveinjury(SNI)modelofSunderlⅡ～Ⅲdegreeweremadeinothertwogroupsbyoperation.OnedayafteroperationwepuncturedHuantiao(GB30)Zusanli(ST36)oftheaffectedsideinEAgroupapplied

5、evenreinfcingreducingbytwirlingrotatingmanipulationtwisteditf30secondseverytimemoveditonetimeper10minutesretainedtheneedlef20minutesoncedailyseventreatmentsmadeacoursetherewasonedaybreakbetweentwocourses.Themodelcontrolg

6、roupwasgraspedeverydaybutwithnotreatment.WeobservedthefunctionofposterirightpawofallanimalsexaminedthecontentofNogoAproteinMAGinthecrespondingspinalcdsegment.Results:(1)AfterfinishingthetreatmentFunctionofinjuredlimbswer

7、eobviouslyimprovedacupuncturetreatmentgroup.(2)AfteratherapeuticcoursethecontentofNogoAproteininacupuncturetreatmentgroupwerehigherthanthatofblankcontrolgroupwhilelowerthanmodelcontrolgrouptherewassignificantdifference(P

8、＜0.05)twocourseslaterthecontentofNogoAproteininacupuncturetreatmentgroupwassignificantlylowerthanthatofmodelcontrolgroup(P＜0.05)therewasnosignificantdifferencewithblankcontrolgroup(P＞0.05).(3)ThecontentofMAGinanterihnofs