兩種去勢治療對晚期前列腺癌患者生活質(zhì)量的影響.pdf

1、溫州醫(yī)學院碩士學位論文兩種去勢治療對晚期前列腺癌患者生活質(zhì)量的影響姓名：陳偉申請學位級別：碩士專業(yè)：外科學（泌尿外科）指導教師：翁志梁20080501墊塑墮堂墮堡主堂垡堡奎一————————————————————————————————————————————————————————一。Healthrelatedqualityoflifeinmanaftertreatmentofadvancedprostatecancerwith2c

2、astrationmethodsAbstractObjectives：1Toinvestigatethehealthrelatedqualityoflifeinmana鑫eftfe破menlofa如褫cedprostatecancerwithsurgicalcastration2Toinvestigatethehealthrelatedqualityoflifeinmanaftertreatmentofadvancedprostatec

3、ancerwithIntermittentAndrogenBlockade(tAB)3。Toevaluate2castrationmethodsaboutthehealthrelatedqualityoflifeinmanofadvancedprostatecancerMethods：1TointroduCtiontheEuropeanOrganizationforResearchandTreatmentofCancerQualityo

4、fLifeQuestionnaire(QLQC30)andQLQ—prostatespecific25item(PR25)module2。Tointroductionthemethodsofletterorout—patientclinicfollowupvisitintheassessmentpoints(beforetreatment，6monthsaftertreatment，12monthsaftertreatmentrespe

5、ctively)3Allpatientsweredividedintotwogroupswithsimplerandomization，groupAteeeivedlAB，andgroupBreceivedSurgicalCastration4Thefindingswerecalculationinalineartransformationandthespss140wasappliedtothescores’SstatisticsRes

6、ults：1AlthoughtherewereimprovementOilpainrelief(PO01)andsymptomofurmaryfP001)andGlobalHealth(Po01)Thephysicalfunctioning(P005)、rolefunctioning(P《O01)、emotionalfunctioning(P《001)、cognitivefunctioning(P005)、socialfunctioni

7、ng(P001)werefoundsignificantlyreduced，andinsomnia(PO05)andfatigue(P001)aggravated，treatmentrelatedsymptoms(P《001)appearedpredominantly，especiallydeprivationofsexualfunctioning2TheFinancialDifficultieswasobviousinlAB，butt

8、hatlessenedduringthetimeofftreatmentProvementswereobservedOilpainrelief(P001)andsym辨鋤ofurinary(P0。01)andGlobalHealth(P001)inpatientstreatedwithlABespeciallyduringthetime—offtreatmentAlthoughthelABcouldaffectsomehealthrel