中藥消疣煎治療尖銳濕疣的臨床研究及對細胞增殖和凋亡的影響.pdf

1、山東中醫(yī)藥大學碩士學位論文中藥消疣煎治療尖銳濕疣的臨床研究及對細胞增殖和凋亡的影響姓名：魏國申請學位級別：碩士專業(yè)：中醫(yī)外科學指導教師：杜錫賢20050420AClinicalstudyoftheChineseMedicineXiaoYouJianintheTreatmeatofCondylomaAcuminatumandtheInfluenceofXiaoYouJianontheproliferationandApoptosisofC

2、ACellsSpeciality：Dermatology，surgeryofTCMAuthor：WeiGuoTutor：DuXixianAbstractObjective：TostudytheclinicaleffectofXiaoYouJian(XYJ)obtainedbythetutorthroughyearsofexperimentsandexploreitsactingmechaniasmTodicusstheinfluence

3、onthecellproliferationandapoptosisofdampandheatfullnesstypecondylomaacuminatum(CA)Methods：96caseswererandomlydividedintotheremedialAgroup，theremedialBgroupandthecontrolgroup，After8weeksoftreatment，observetheclinicalcurer

4、ateandrelapserateaswellastheabnormalreactionApplyimmuneorganismchemotherapyandTUNELtherapyto15casesingroupA，examinethewartsformedbeforethemedicine—washand2weekslaterrespectiveIvtakecountofthePCNAandthenumberofdeceasedcel

5、lsandcompareitwiththatofahealthybodyResult：Thecurerateofthetreatmentgroup(groupA806％，groupB83_3％)ismuchhigherwhiletherelapserateislowerthanthatofthecontrastivegroupwimaremarkablediscrepancyPCNAisgreatlyreducedwhileapopto

6、siscellsincreased2weekslaterthanbeforethetreatmentThediscrepancyofthetwobothhasstatisticalsignificanceConclusion：Thesedataindicatethatremove—wartandmedicinewashtherapycanimprovethecurerateofdampandheatfullnesstypecondylo

7、maacuminatum，reducetherelapserateandatthesametimenotangiblesideeffectsarenoticedItsmechanismprobablyfunctionthroughcongo]lingthemultiplicationofcellsandspeeduptheapoptosisofcellsKeywords：Condylomaacuminatum；TherapyofTCM；